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Use of FVB Myc-CaP cells as an immune competent, androgen receptor positive, mouse model of prostate cancer bone metastasis

Prostate cancer (PCa) metastasis research has been hamstrung by lack of animal models that closely resemble the disease present in most patients – that metastasize to bone, are dependent on the androgen receptor (AR), and grow in an immune competent host. Here, we adapt the Myc-CaP cell line for use...

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Detalles Bibliográficos
Autores principales: Wang, Yu, Herroon, Mackenzie K., Zielske, Steven P., Ellis, Leigh, Podgorski, Izabela, Taichman, Russell S., Cackowski, Frank C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8385442/
https://www.ncbi.nlm.nih.gov/pubmed/34466376
http://dx.doi.org/10.1016/j.jbo.2021.100386