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Expression and Localization of AβPP in SH-SY5Y Cells Depends on Differentiation State

Neuroblastoma cell line SH-SY5Y, due to its capacity to differentiate into neurons, easy handling, and low cost, is a common experimental model to study molecular events leading to Alzheimer’s disease (AD). However, it is prevalently used in its undifferentiated state, which does not resemble neuron...

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Detalles Bibliográficos
Autores principales: Riegerová, Petra, Brejcha, Jindřich, Bezděková, Dagmar, Chum, Tomáš, Mašínová, Eva, Čermáková, Nikola, Ovsepian, Saak V., Cebecauer, Marek, Štefl, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: IOS Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8385523/
https://www.ncbi.nlm.nih.gov/pubmed/34057078
http://dx.doi.org/10.3233/JAD-201409