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Spatiotemporal and Functional Heterogeneity of Hematopoietic Stem Cell-Competent Hemogenic Endothelial Cells in Mouse Embryos

Hematopoietic stem cells (HSCs) are derived from hemogenic endothelial cells (HECs) during embryogenesis. The HSC-primed HECs increased to the peak at embryonic day (E) 10 and have been efficiently captured by the marker combination CD41(–)CD43(–)CD45(–)CD31(+)CD201(+)Kit(+)CD44(+) (PK44) in the aor...

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Detalles Bibliográficos
Autores principales: Li, Yun-Qiao, Gong, Yandong, Hou, Siyuan, Huang, Tao, Wang, Haizhen, Liu, Di, Ni, Yanli, Wang, Chaojie, Wang, Junliang, Hou, Jun, Yang, Ruichuang, Yan, Jing, Zhang, Guangyu, Liu, Bing, Lan, Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8385538/
https://www.ncbi.nlm.nih.gov/pubmed/34458261
http://dx.doi.org/10.3389/fcell.2021.699263