Fluorescence Correlation Spectroscopy Reveals Survival Motor Neuron Oligomerization but No Active Transport in Motor Axons of a Zebrafish Model for Spinal Muscular Atrophy

Spinal Muscular Atrophy (SMA) is a progressive neurodegenerative disease affecting lower motor neurons that is caused by a deficiency in ubiquitously expressed Survival Motor Neuron (SMN) protein. Two mutually exclusive hypotheses have been discussed to explain increased motor neuron vulnerability i...

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Detalles Bibliográficos
Autores principales: Koh, Angela, Sarusie, Menachem Viktor, Ohmer, Jürgen, Fischer, Utz, Winkler, Christoph, Wohland, Thorsten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8385639/
https://www.ncbi.nlm.nih.gov/pubmed/34458251
http://dx.doi.org/10.3389/fcell.2021.639904

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8385639/
https://www.ncbi.nlm.nih.gov/pubmed/34458251
http://dx.doi.org/10.3389/fcell.2021.639904

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