Cargando…
Fluorescence Correlation Spectroscopy Reveals Survival Motor Neuron Oligomerization but No Active Transport in Motor Axons of a Zebrafish Model for Spinal Muscular Atrophy
Spinal Muscular Atrophy (SMA) is a progressive neurodegenerative disease affecting lower motor neurons that is caused by a deficiency in ubiquitously expressed Survival Motor Neuron (SMN) protein. Two mutually exclusive hypotheses have been discussed to explain increased motor neuron vulnerability i...
Autores principales: | Koh, Angela, Sarusie, Menachem Viktor, Ohmer, Jürgen, Fischer, Utz, Winkler, Christoph, Wohland, Thorsten |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8385639/ https://www.ncbi.nlm.nih.gov/pubmed/34458251 http://dx.doi.org/10.3389/fcell.2021.639904 |
Ejemplares similares
-
Embryonic motor activity and implications for regulating motoneuron axonal pathfinding in zebrafish
por: Menelaou, Evdokia, et al.
Publicado: (2008) -
Small Molecule Suppressors of Drosophila Kinesin Deficiency Rescue Motor Axon Development in a Zebrafish Model of Spinal Muscular Atrophy
por: Gassman, Andrew, et al.
Publicado: (2013) -
Multifaceted roles of microRNAs: From motor neuron generation in embryos to degeneration in spinal muscular atrophy
por: Chen, Tai-Heng, et al.
Publicado: (2019) -
Mid1 is associated with androgen-dependent axonal vulnerability of motor neurons in spinal and bulbar muscular atrophy
por: Ogura, Yosuke, et al.
Publicado: (2022) -
Hypergravity hinders axonal development of motor neurons in Caenorhabditis elegans
por: Kalichamy, Saraswathi Subbammal, et al.
Publicado: (2016)