ACE2-targeting monoclonal antibody as potent and broad-spectrum coronavirus blocker

The evolution of coronaviruses, such as SARS-CoV-2, makes broad-spectrum coronavirus preventional or therapeutical strategies highly sought after. Here we report a human angiotensin-converting enzyme 2 (ACE2)-targeting monoclonal antibody, 3E8, blocked the S1-subunits and pseudo-typed virus construc...

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Detalles Bibliográficos
Autores principales: Chen, Yuning, Zhang, Ya-Nan, Yan, Renhong, Wang, Guifeng, Zhang, Yuanyuan, Zhang, Zhe-Rui, Li, Yaning, Ou, Jianxia, Chu, Wendi, Liang, Zhijuan, Wang, Yongmei, Chen, Yi-Li, Chen, Ganjun, Wang, Qi, Zhou, Qiang, Zhang, Bo, Wang, Chunhe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8385704/
https://www.ncbi.nlm.nih.gov/pubmed/34433803
http://dx.doi.org/10.1038/s41392-021-00740-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8385704/
https://www.ncbi.nlm.nih.gov/pubmed/34433803
http://dx.doi.org/10.1038/s41392-021-00740-y

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