Correction of Vertebral Bone Development in Ectodysplasin A1-Deficient Mice by Prenatal Treatment With a Replacement Protein

X-linked hypohidrotic ectodermal dysplasia with the cardinal symptoms hypodontia, hypotrichosis and hypohidrosis is caused by a genetic deficiency of ectodysplasin A1 (EDA1). Prenatal EDA1 replacement can rescue the development of skin appendages and teeth. Tabby mice, a natural animal model of EDA1...

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Detalles Bibliográficos
Autores principales: Kossel, Clara-Sophie, Wahlbuhl, Mandy, Schuepbach-Mallepell, Sonia, Park, Jung, Kowalczyk-Quintas, Christine, Seeling, Michaela, von der Mark, Klaus, Schneider, Pascal, Schneider, Holm
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Genetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8385758/
https://www.ncbi.nlm.nih.gov/pubmed/34456978
http://dx.doi.org/10.3389/fgene.2021.709736

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8385758/
https://www.ncbi.nlm.nih.gov/pubmed/34456978
http://dx.doi.org/10.3389/fgene.2021.709736

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