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The Phage T4 Antiholin RI Has a Cleavable Signal Peptide, Not a SAR Domain

Holin/endolysin-mediated lysis of phage T4 of Escherichia coli is tightly regulated by the antiholins RI and RIII. While regulation by the cytoplasmic RIII plays a minor role, the periplasmic antiholin RI binds tightly to the holin T and is believed to directly sense periplasmic phage DNA from super...

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Detalles Bibliográficos
Autores principales: Mehner-Breitfeld, Denise, Schwarzkopf, Jan Michel Frederik, Young, Ry, Kondabagil, Kiran, Brüser, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8385771/
https://www.ncbi.nlm.nih.gov/pubmed/34456892
http://dx.doi.org/10.3389/fmicb.2021.712460