Acute depletion of CTCF rewires genome-wide chromatin accessibility

BACKGROUND: The transcription factor CTCF appears indispensable in defining topologically associated domain boundaries and maintaining chromatin loop structures within these domains, supported by numerous functional studies. However, acute depletion of CTCF globally reduces chromatin interactions bu...

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Detalles Bibliográficos
Autores principales: Xu, Beisi, Wang, Hong, Wright, Shaela, Hyle, Judith, Zhang, Yang, Shao, Ying, Niu, Mingming, Fan, Yiping, Rosikiewicz, Wojciech, Djekidel, Mohamed Nadhir, Peng, Junmin, Lu, Rui, Li, Chunliang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8386078/
https://www.ncbi.nlm.nih.gov/pubmed/34429148
http://dx.doi.org/10.1186/s13059-021-02466-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8386078/
https://www.ncbi.nlm.nih.gov/pubmed/34429148
http://dx.doi.org/10.1186/s13059-021-02466-0

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