Cyclic peptide scaffold with ability to stabilize and deliver a helical cell-impermeable cargo across membranes of cultured cancer cells

Cell penetrating peptides (CPPs) are valuable tools for developing anticancer therapies due to their ability to access intracellular targets, including protein–protein interactions. cPF4PD is a newly described CPP designed from a transduction domain of the human defense protein platelet factor 4 (PF...

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Detalles Bibliográficos
Autores principales: Lawrence, Nicole, Philippe, Grégoire J.-B., Harvey, Peta J., Condon, Nicholas D., Benfield, Aurélie H., Cheneval, Olivier, Craik, David J., Troeira Henriques, Sónia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: RSC 2020
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8386104/
https://www.ncbi.nlm.nih.gov/pubmed/34458771
http://dx.doi.org/10.1039/d0cb00099j

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8386104/
https://www.ncbi.nlm.nih.gov/pubmed/34458771
http://dx.doi.org/10.1039/d0cb00099j

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