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A novel non-viral delivery method that enables efficient engineering of primary human T cells for ex vivo cell therapy applications

BACKGROUND AIMS: Next-generation immune cell therapy products will require complex modifications using engineering technologies that can maintain high levels of cell functionality. Non-viral engineering methods have the potential to address limitations associated with viral vectors. However, while e...

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Detalles Bibliográficos
Autores principales: Kavanagh, Heather, Dunne, Susan, Martin, Darren S., McFadden, Emily, Gallagher, Louise, Schwaber, Jessica, Leonard, Siobhán, O'Dea, Shirley
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8386197/
https://www.ncbi.nlm.nih.gov/pubmed/33941482
http://dx.doi.org/10.1016/j.jcyt.2021.03.002