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Molecular signatures of aggressive pediatric liver cancer

1. Conversion of tumor suppressor proteins (TSPs) by posttranslational modifications into oncogenes. 2. Activation of specific chromosomal regions, i.e., Aggressive Liver Cancer Domains (ALCDs) within many oncogenes, resulting in increased expression of oncogenes. 3. Potential epigenetic mechanisms...

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Detalles Bibliográficos
Autores principales: Johnston, Michael E., Timchenko, Nikolai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8386353/
https://www.ncbi.nlm.nih.gov/pubmed/34447970