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Establishment of a Patient-Derived, Magnetic Levitation-Based, Three-Dimensional Spheroid Granuloma Model for Human Tuberculosis

Tuberculous granulomas that develop in response to Mycobacterium tuberculosis (M. tuberculosis) infection are highly dynamic entities shaped by the host immune response and disease kinetics. Within this microenvironment, immune cell recruitment, polarization, and activation are driven not only by co...

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Detalles Bibliográficos
Autores principales: Kotze, Leigh A., Beltran, Caroline G. G., Lang, Dirk, Loxton, Andre G., Cooper, Susan, Meiring, Maynard, Koegelenberg, Coenraad F. N., Allwood, Brian W., Malherbe, Stephanus T., Hiemstra, Andriette M., Glanzmann, Brigitte, Kinnear, Craig, Walzl, Gerhard, du Plessis, Nelita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8386456/
https://www.ncbi.nlm.nih.gov/pubmed/34287004
http://dx.doi.org/10.1128/mSphere.00552-21