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Establishment of a Patient-Derived, Magnetic Levitation-Based, Three-Dimensional Spheroid Granuloma Model for Human Tuberculosis
Tuberculous granulomas that develop in response to Mycobacterium tuberculosis (M. tuberculosis) infection are highly dynamic entities shaped by the host immune response and disease kinetics. Within this microenvironment, immune cell recruitment, polarization, and activation are driven not only by co...
Autores principales: | Kotze, Leigh A., Beltran, Caroline G. G., Lang, Dirk, Loxton, Andre G., Cooper, Susan, Meiring, Maynard, Koegelenberg, Coenraad F. N., Allwood, Brian W., Malherbe, Stephanus T., Hiemstra, Andriette M., Glanzmann, Brigitte, Kinnear, Craig, Walzl, Gerhard, du Plessis, Nelita |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8386456/ https://www.ncbi.nlm.nih.gov/pubmed/34287004 http://dx.doi.org/10.1128/mSphere.00552-21 |
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