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Development and validation of an intra-tumor heterogeneity-related signature to predict prognosis of bladder cancer: a study based on single-cell RNA-seq

Intra-tumor heterogeneity (ITH) was a potential mechanism of progression and drug resistance in bladder cancer (BCa). However, the understanding of ITH in BCa remains insufficient. Single-cell RNA sequencing (scRNA-seq) profiles of 2075 cells were analyzed, and 2940 cell markers were screened. The I...

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Detalles Bibliográficos
Autores principales: Zhou, Ranran, Liang, Jingjing, Chen, Qi, Tian, Hu, Yang, Cheng, Liu, Cundong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8386527/
https://www.ncbi.nlm.nih.gov/pubmed/34339395
http://dx.doi.org/10.18632/aging.203353