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Endothelium-specific deletion of amyloid-β precursor protein exacerbates endothelial dysfunction induced by aging
The physiological function of amyloid precursor protein (APP) in the control of endothelial function during aging is unclear. Aortas of young (4-6 months old) and aged (23-26 months old) wild-type (WT) and endothelium-specific APP-deficient (eAPP(−/−)) mice were used to study aging-induced changes i...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Impact Journals
2021
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8386539/ https://www.ncbi.nlm.nih.gov/pubmed/34382945 http://dx.doi.org/10.18632/aging.203401 |