miRNA-221-3p derived from M2-polarized tumor-associated macrophage exosomes aggravates the growth and metastasis of osteosarcoma through SOCS3/JAK2/STAT3 axis

Background: Enhanced infiltration of M2-polarized tumor-associated macrophages (TAMs) is linked to osteosarcoma (OS) metastasis and growth. Here, we aim to explore a novel miR-221-3p shuttled by M2-TAM exosomes in the growth and metastasis of OS cells. Methods: THP-1 monocytes-derived M2-TAMs were i...

Descripción completa

Detalles Bibliográficos
Autores principales: Liu, Wei, Long, Qiuping, Zhang, Wei, Zeng, Dehui, Hu, Bingbing, Liu, Shengyao, Chen, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8386545/
https://www.ncbi.nlm.nih.gov/pubmed/34388111
http://dx.doi.org/10.18632/aging.203388

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8386545/
https://www.ncbi.nlm.nih.gov/pubmed/34388111
http://dx.doi.org/10.18632/aging.203388

Ejemplares similares