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miRNA-221-3p derived from M2-polarized tumor-associated macrophage exosomes aggravates the growth and metastasis of osteosarcoma through SOCS3/JAK2/STAT3 axis

Background: Enhanced infiltration of M2-polarized tumor-associated macrophages (TAMs) is linked to osteosarcoma (OS) metastasis and growth. Here, we aim to explore a novel miR-221-3p shuttled by M2-TAM exosomes in the growth and metastasis of OS cells. Methods: THP-1 monocytes-derived M2-TAMs were i...

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Detalles Bibliográficos
Autores principales:	Liu, Wei, Long, Qiuping, Zhang, Wei, Zeng, Dehui, Hu, Bingbing, Liu, Shengyao, Chen, Li
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals 2021
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8386545/ https://www.ncbi.nlm.nih.gov/pubmed/34388111 http://dx.doi.org/10.18632/aging.203388

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