Dual inhibition of FGFR4 and BCL-xL inhibits multi-resistant ovarian cancer with BCL2L1 gain

Aim: Overexpression of BCL2L1 (BCL-xL) was associated with platinum resistance in ovarian cancer (OvCa). However, role of copy number (CN) gain of BCL2L1 in OvCa remains elusive. Methods: In silico analyses of multiple public datasets were perform. Validation was carried out in our tissue microarray...

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Detalles Bibliográficos
Autores principales: Guo, Ting, Gu, Chao, Li, Bin, Xu, Congjian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8386571/
https://www.ncbi.nlm.nih.gov/pubmed/34351305
http://dx.doi.org/10.18632/aging.203386

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8386571/
https://www.ncbi.nlm.nih.gov/pubmed/34351305
http://dx.doi.org/10.18632/aging.203386

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