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Mice deficient in UXT exhibit retinitis pigmentosa-like features via aberrant autophagy activation

UXT (ubiquitously expressed prefoldin like chaperone), a small chaperone-like protein, is widely expressed in diverse human and mouse tissues and is more abundant in retina and kidney. However, the functional characterization of UXT at tissue level was largely unknown. Here, we reported that mice de...

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Detalles Bibliográficos
Autores principales: Pan, Mingyu, Yin, Yue, Wang, Xinxia, Wang, Quanyi, Zhang, Lele, Hu, Haiyang, Wang, Chen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8386600/
https://www.ncbi.nlm.nih.gov/pubmed/32744119
http://dx.doi.org/10.1080/15548627.2020.1796015