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The GID ubiquitin ligase complex is a regulator of AMPK activity and organismal lifespan

The AMP-activated protein kinase (AMPK) regulates cellular energy homeostasis by sensing the metabolic status of the cell. AMPK is regulated by phosphorylation and dephosphorylation as a result of changing AMP/ATP levels and by removal of inhibitory ubiquitin residues by USP10. In this context, we i...

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Detalles Bibliográficos
Autores principales: Liu, Huaize, Ding, Jie, Köhnlein, Karl, Urban, Nadine, Ori, Alessandro, Villavicencio-Lorini, Pablo, Walentek, Peter, Klotz, Lars-Oliver, Hollemann, Thomas, Pfirrmann, Thorsten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8386601/
https://www.ncbi.nlm.nih.gov/pubmed/31795790
http://dx.doi.org/10.1080/15548627.2019.1695399