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The GID ubiquitin ligase complex is a regulator of AMPK activity and organismal lifespan
The AMP-activated protein kinase (AMPK) regulates cellular energy homeostasis by sensing the metabolic status of the cell. AMPK is regulated by phosphorylation and dephosphorylation as a result of changing AMP/ATP levels and by removal of inhibitory ubiquitin residues by USP10. In this context, we i...
Autores principales: | Liu, Huaize, Ding, Jie, Köhnlein, Karl, Urban, Nadine, Ori, Alessandro, Villavicencio-Lorini, Pablo, Walentek, Peter, Klotz, Lars-Oliver, Hollemann, Thomas, Pfirrmann, Thorsten |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8386601/ https://www.ncbi.nlm.nih.gov/pubmed/31795790 http://dx.doi.org/10.1080/15548627.2019.1695399 |
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