TGFB-INHB/activin signaling regulates age-dependent autophagy and cardiac health through inhibition of MTORC2

Age-related impairment of macroautophagy/autophagy and loss of cardiac tissue homeostasis contribute significantly to cardiovascular diseases later in life. MTOR (mechanistic target of rapamycin kinase) signaling is the most well-known regulator of autophagy, cellular homeostasis, and longevity. The...

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Detalles Bibliográficos
Autores principales: Chang, Kai, Kang, Ping, Liu, Ying, Huang, Kerui, Miao, Ting, Sagona, Antonia P., Nezis, Ioannis P., Bodmer, Rolf, Ocorr, Karen, Bai, Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2019
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8386626/
https://www.ncbi.nlm.nih.gov/pubmed/31884871
http://dx.doi.org/10.1080/15548627.2019.1704117

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8386626/
https://www.ncbi.nlm.nih.gov/pubmed/31884871
http://dx.doi.org/10.1080/15548627.2019.1704117

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