Mechanistic insights into dopaminergic and serotonergic neurotransmission – concerted interactions with helices 5 and 6 drive the functional outcome

Brain functions rely on neurotransmitters that mediate communication between billions of neurons. Disruption of this communication can result in a plethora of psychiatric and neurological disorders. In this work, we combine molecular dynamics simulations, live-cell biosensor and electrophysiological...

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Detalles Bibliográficos
Autores principales: Stepniewski, Tomasz Maciej, Mancini, Arturo, Ågren, Richard, Torrens-Fontanals, Mariona, Semache, Meriem, Bouvier, Michel, Sahlholm, Kristoffer, Breton, Billy, Selent, Jana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2021
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8386650/
https://www.ncbi.nlm.nih.gov/pubmed/34522296
http://dx.doi.org/10.1039/d1sc00749a

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8386650/
https://www.ncbi.nlm.nih.gov/pubmed/34522296
http://dx.doi.org/10.1039/d1sc00749a

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