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Conformational interplay in hybrid peptide–helical aromatic foldamer macrocycles

Macrocyclic peptides are an important class of bioactive substances. When inserting an aromatic foldamer segment in a macrocyclic peptide, the strong folding propensity of the former may influence the conformation and alter the properties of the latter. Such an insertion is relevant because some fol...

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Detalles Bibliográficos
Autores principales: Dengler, Sebastian, Mandal, Pradeep K., Allmendinger, Lars, Douat, Céline, Huc, Ivan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8386670/
https://www.ncbi.nlm.nih.gov/pubmed/34522297
http://dx.doi.org/10.1039/d1sc03640h