Pharmacological suppression of the WNT signaling pathway attenuates age-dependent expression of the phenotype in a mouse model of arrhythmogenic cardiomyopathy

INTRODUCTION: Arrhythmogenic cardiomyopathy (ACM) is a genetic disease of the myocardium, characterized by cardiac arrhythmias, dysfunction, and sudden cardiac death. The pathological hallmark of ACM is fibro-adipocytes replacing cardiac myocytes. The canonical WNT pathway is implicated in the patho...

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Detalles Bibliográficos
Autores principales: Cheedipudi, Sirisha M., Fan, Siyang, Rouhi, Leila, Marian, Ali J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8386676/
https://www.ncbi.nlm.nih.gov/pubmed/34447973
http://dx.doi.org/10.20517/jca.2021.04

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8386676/
https://www.ncbi.nlm.nih.gov/pubmed/34447973
http://dx.doi.org/10.20517/jca.2021.04

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