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G6pd-Deficient Mice Are Protected From Experimental Cerebral Malaria and Liver Injury by Suppressing Proinflammatory Response in the Early Stage of Plasmodium berghei Infection

Epidemiological studies provide compelling evidence that glucose-6-phosphate dehydrogenase (G6PD) deficiency individuals are relatively protected against Plasmodium parasite infection. However, the animal model studies on this subject are lacking. Plus, the underlying mechanism in vivo is poorly kno...

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Detalles Bibliográficos
Autores principales: Yi, Haoan, Jiang, Weiyang, Yang, Fang, Li, Fan, Li, Yirong, Zhu, Wenjing, Li, Qing, Fakhar, Syed Hassam, Cao, Yaming, Luo, Lan, Zhang, Wen, He, Yongshu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8386684/
https://www.ncbi.nlm.nih.gov/pubmed/34456927
http://dx.doi.org/10.3389/fimmu.2021.719189