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Proliferative stem cells maintain quiescence of their niche by secreting the Activin inhibitor Follistatin

Aging causes stem cell dysfunction as a result of extrinsic and intrinsic changes. Decreased function of the stem cell niche is an important contributor to this dysfunction. We use the Drosophila testis to investigate what factors maintain niche cells. The testis niche comprises quiescent “hub” cell...

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Detalles Bibliográficos
Autores principales: Herrera, Salvador C., Sainz de la Maza, Diego, Grmai, Lydia, Margolis, Shally, Plessel, Rebecca, Burel, Michael, O’Connor, Michael, Amoyel, Marc, Bach, Erika A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8387025/
https://www.ncbi.nlm.nih.gov/pubmed/34363758
http://dx.doi.org/10.1016/j.devcel.2021.07.010