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Proliferative stem cells maintain quiescence of their niche by secreting the Activin inhibitor Follistatin
Aging causes stem cell dysfunction as a result of extrinsic and intrinsic changes. Decreased function of the stem cell niche is an important contributor to this dysfunction. We use the Drosophila testis to investigate what factors maintain niche cells. The testis niche comprises quiescent “hub” cell...
Autores principales: | Herrera, Salvador C., Sainz de la Maza, Diego, Grmai, Lydia, Margolis, Shally, Plessel, Rebecca, Burel, Michael, O’Connor, Michael, Amoyel, Marc, Bach, Erika A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8387025/ https://www.ncbi.nlm.nih.gov/pubmed/34363758 http://dx.doi.org/10.1016/j.devcel.2021.07.010 |
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