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Structures of Substrate Complexes of Foamy Viral Protease-Reverse Transcriptase

Reverse transcriptases (RTs) use their DNA polymerase and RNase H activities to catalyze the conversion of single-stranded RNA to double-stranded DNA (dsDNA), a crucial process for the replication of retroviruses. Foamy viruses (FVs) possess a unique RT, which is a fusion with the protease (PR) doma...

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Detalles Bibliográficos
Autores principales: Nowacka, Marzena, Nowak, Elżbieta, Czarnocki-Cieciura, Mariusz, Jackiewicz, Justyna, Skowronek, Krzysztof, Szczepanowski, Roman H., Wöhrl, Birgitta M., Nowotny, Marcin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8387031/
https://www.ncbi.nlm.nih.gov/pubmed/34232702
http://dx.doi.org/10.1128/JVI.00848-21