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Structures of Substrate Complexes of Foamy Viral Protease-Reverse Transcriptase
Reverse transcriptases (RTs) use their DNA polymerase and RNase H activities to catalyze the conversion of single-stranded RNA to double-stranded DNA (dsDNA), a crucial process for the replication of retroviruses. Foamy viruses (FVs) possess a unique RT, which is a fusion with the protease (PR) doma...
Autores principales: | Nowacka, Marzena, Nowak, Elżbieta, Czarnocki-Cieciura, Mariusz, Jackiewicz, Justyna, Skowronek, Krzysztof, Szczepanowski, Roman H., Wöhrl, Birgitta M., Nowotny, Marcin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8387031/ https://www.ncbi.nlm.nih.gov/pubmed/34232702 http://dx.doi.org/10.1128/JVI.00848-21 |
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