Protective Role of 4-Octyl Itaconate in Murine LPS/D-GalN-Induced Acute Liver Failure via Inhibiting Inflammation, Oxidative Stress, and Apoptosis

Oxidative stress, inflammation, and apoptosis are crucial in the pathogenesis of acute liver failure (ALF). 4-Octyl itaconate (OI) showed antioxidative and anti-inflammatory properties in many disease models. However, its role in lipopolysaccharide- (LPS-)/D-galactosamine- (D-GalN-) induced ALF is s...

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Detalles Bibliográficos
Autores principales: Li, Ruidong, Yang, Wenchang, Yin, Yuping, Zhang, Peng, Wang, Yaxin, Tao, Kaixiong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8387163/
https://www.ncbi.nlm.nih.gov/pubmed/34457120
http://dx.doi.org/10.1155/2021/9932099

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8387163/
https://www.ncbi.nlm.nih.gov/pubmed/34457120
http://dx.doi.org/10.1155/2021/9932099

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