Cargando…
Protective Role of 4-Octyl Itaconate in Murine LPS/D-GalN-Induced Acute Liver Failure via Inhibiting Inflammation, Oxidative Stress, and Apoptosis
Oxidative stress, inflammation, and apoptosis are crucial in the pathogenesis of acute liver failure (ALF). 4-Octyl itaconate (OI) showed antioxidative and anti-inflammatory properties in many disease models. However, its role in lipopolysaccharide- (LPS-)/D-galactosamine- (D-GalN-) induced ALF is s...
Autores principales: | Li, Ruidong, Yang, Wenchang, Yin, Yuping, Zhang, Peng, Wang, Yaxin, Tao, Kaixiong |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8387163/ https://www.ncbi.nlm.nih.gov/pubmed/34457120 http://dx.doi.org/10.1155/2021/9932099 |
Ejemplares similares
-
Hepatoprotective Role of 4-Octyl Itaconate in Concanavalin A-Induced Autoimmune Hepatitis
por: Yang, Wenchang, et al.
Publicado: (2022) -
Metabolite itaconate in host immunoregulation and defense
por: Yang, Wenchang, et al.
Publicado: (2023) -
Protective effects of IRG1/itaconate on acute colitis through the inhibition of gasdermins-mediated pyroptosis and inflammation response
por: Yang, Wenchang, et al.
Publicado: (2022) -
4-Octyl itaconate regulates immune balance by activating Nrf2 and negatively regulating PD-L1 in a mouse model of sepsis
por: Zhang, Peng, et al.
Publicado: (2022) -
BML-111 Protected LPS/D-GalN-Induced Acute Liver Injury in Rats
por: Yan, Dan, et al.
Publicado: (2016)