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Leptin Induced TLR4 Expression via the JAK2-STAT3 Pathway in Obesity-Related Osteoarthritis

Obesity is considered as a risk factor of osteoarthritis (OA), but the precise relationship is still poorly understood. Leptin, one of the most relevant factors secreted by adipose tissues, plays an important role in the pathogenesis of OA. Our aim was to investigate the regulation and molecular mec...

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Detalles Bibliográficos
Autores principales: Jiang, Mengqi, He, Jianyi, Sun, Yingxu, Dong, Xin, Yao, Jiayu, Gu, Hailun, Liu, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8387187/
https://www.ncbi.nlm.nih.gov/pubmed/34457118
http://dx.doi.org/10.1155/2021/7385160