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Leptin Induced TLR4 Expression via the JAK2-STAT3 Pathway in Obesity-Related Osteoarthritis
Obesity is considered as a risk factor of osteoarthritis (OA), but the precise relationship is still poorly understood. Leptin, one of the most relevant factors secreted by adipose tissues, plays an important role in the pathogenesis of OA. Our aim was to investigate the regulation and molecular mec...
Autores principales: | Jiang, Mengqi, He, Jianyi, Sun, Yingxu, Dong, Xin, Yao, Jiayu, Gu, Hailun, Liu, Li |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8387187/ https://www.ncbi.nlm.nih.gov/pubmed/34457118 http://dx.doi.org/10.1155/2021/7385160 |
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