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Expression of CYP24A1 and other multiple sclerosis risk genes in peripheral blood indicates response to vitamin D in homeostatic and inflammatory conditions

Although genetic and epidemiological evidence indicates vitamin D insufficiency contributes to multiple sclerosis (MS), and serum levels of vitamin D increase on treatment with cholecalciferol, recent metanalyses indicate that this vitamin D form does not ameliorate disease. Genetic variation in gen...

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Detalles Bibliográficos
Autores principales: Law, Samantha P. L., Gatt, Prudence N., Schibeci, Stephen D., McKay, Fiona C., Vucic, Steve, Hart, Prue, Byrne, Scott N., Brown, David, Stewart, Graeme J., Liddle, Christopher, Parnell, Grant P., Booth, David R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8387232/
https://www.ncbi.nlm.nih.gov/pubmed/34163021
http://dx.doi.org/10.1038/s41435-021-00144-6