Cargando…
Expression of CYP24A1 and other multiple sclerosis risk genes in peripheral blood indicates response to vitamin D in homeostatic and inflammatory conditions
Although genetic and epidemiological evidence indicates vitamin D insufficiency contributes to multiple sclerosis (MS), and serum levels of vitamin D increase on treatment with cholecalciferol, recent metanalyses indicate that this vitamin D form does not ameliorate disease. Genetic variation in gen...
Autores principales: | Law, Samantha P. L., Gatt, Prudence N., Schibeci, Stephen D., McKay, Fiona C., Vucic, Steve, Hart, Prue, Byrne, Scott N., Brown, David, Stewart, Graeme J., Liddle, Christopher, Parnell, Grant P., Booth, David R. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8387232/ https://www.ncbi.nlm.nih.gov/pubmed/34163021 http://dx.doi.org/10.1038/s41435-021-00144-6 |
Ejemplares similares
-
IL7Rα Expression and Upregulation by IFNβ in Dendritic Cell Subsets Is Haplotype-Dependent
por: McKay, Fiona C., et al.
Publicado: (2013) -
The MS Risk Allele of CD40 Is Associated with Reduced Cell-Membrane Bound Expression in Antigen Presenting Cells: Implications for Gene Function
por: Field, Judith, et al.
Publicado: (2015) -
Differences in common heritable blood immune cell populations may underlie MS susceptibility and progression
por: Booth, David R, et al.
Publicado: (2016) -
Evidence from genome wide association studies implicates reduced control of Epstein-Barr virus infection in multiple sclerosis susceptibility
por: Afrasiabi, Ali, et al.
Publicado: (2019) -
Age-dependent VDR peak DNA methylation as a mechanism for latitude-dependent multiple sclerosis risk
por: Ong, Lawrence T. C., et al.
Publicado: (2021)