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Salts and Polymorph Screens for Bedaquiline

Bedaquiline is used to treat multi-resistant tuberculosis in adults. The fumarate salt is commercially available and used in the product Sirturo. To provide open access to bedaquiline molecule once the patent on the chemical substance expires, new salts were screened. This work offers additional inf...

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Detalles Bibliográficos
Autores principales: Okezue, Mercy, Bogdanowich-Knipp, Susan, Smith, Daniel, Zeller, Matthias, Byrn, Stephen, Smith, Pamela, Purcell, Dale K., Clase, Kari
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8387259/
https://www.ncbi.nlm.nih.gov/pubmed/34435280
http://dx.doi.org/10.1208/s12249-021-02106-7