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Salts and Polymorph Screens for Bedaquiline
Bedaquiline is used to treat multi-resistant tuberculosis in adults. The fumarate salt is commercially available and used in the product Sirturo. To provide open access to bedaquiline molecule once the patent on the chemical substance expires, new salts were screened. This work offers additional inf...
Autores principales: | Okezue, Mercy, Bogdanowich-Knipp, Susan, Smith, Daniel, Zeller, Matthias, Byrn, Stephen, Smith, Pamela, Purcell, Dale K., Clase, Kari |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8387259/ https://www.ncbi.nlm.nih.gov/pubmed/34435280 http://dx.doi.org/10.1208/s12249-021-02106-7 |
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