Reduced nitric oxide bioavailability impairs myocardial oxygen balance during exercise in swine with multiple risk factors

In the present study, we tested the hypothesis that multiple risk factors, including diabetes mellitus (DM), dyslipidaemia and chronic kidney disease (CKD) result in a loss of nitric oxide (NO) signalling, thereby contributing to coronary microvascular dysfunction. Risk factors were induced in 12 fe...

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Detalles Bibliográficos
Autores principales: van de Wouw, Jens, Sorop, Oana, van Drie, Ruben W. A., Joles, Jaap A., Danser, A. H. Jan, Verhaar, Marianne C., Merkus, Daphne, Duncker, Dirk J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2021
Materias:
Original Contribution
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8387273/
https://www.ncbi.nlm.nih.gov/pubmed/34435256
http://dx.doi.org/10.1007/s00395-021-00890-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8387273/
https://www.ncbi.nlm.nih.gov/pubmed/34435256
http://dx.doi.org/10.1007/s00395-021-00890-8

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