Chitosan-Poly(Acrylic Acid) Nanoparticles Loaded with R848 and MnCl(2) Inhibit Melanoma via Regulating Macrophage Polarization and Dendritic Cell Maturation

PURPOSE: Since immune cells in the tumor microenvironment (TME) can affect the development and progression of tumors, strategies modulating immune cells are considered to have an important therapeutic effect. As a TLR7/8 agonist, R848 effectively activates the innate immune cells to exert an anti-tu...

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Detalles Bibliográficos
Autores principales: Liu, Xinghan, Xu, Yujun, Yin, Lijie, Hou, Yayi, Zhao, Shuli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8387326/
https://www.ncbi.nlm.nih.gov/pubmed/34456564
http://dx.doi.org/10.2147/IJN.S318363

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8387326/
https://www.ncbi.nlm.nih.gov/pubmed/34456564
http://dx.doi.org/10.2147/IJN.S318363

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