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Reelin depletion alleviates multiple myeloma bone disease by promoting osteogenesis and inhibiting osteolysis
Extracellular matrix glycoprotein Reelin is associated with tumor metastasis and prognosis in various malignancies. However, its effects on multiple myeloma (MM) are not fully understood. Here, we investigated the regulatory effects of Reelin on MM and its underlying pathogenic mechanisms. Lentiviru...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8387418/ https://www.ncbi.nlm.nih.gov/pubmed/34433809 http://dx.doi.org/10.1038/s41420-021-00608-8 |