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Reelin depletion alleviates multiple myeloma bone disease by promoting osteogenesis and inhibiting osteolysis

Extracellular matrix glycoprotein Reelin is associated with tumor metastasis and prognosis in various malignancies. However, its effects on multiple myeloma (MM) are not fully understood. Here, we investigated the regulatory effects of Reelin on MM and its underlying pathogenic mechanisms. Lentiviru...

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Detalles Bibliográficos
Autores principales: Dou, Aixia, Zhang, Ying, Wang, Yongjing, Liu, Xiaoli, Guo, Yanan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8387418/
https://www.ncbi.nlm.nih.gov/pubmed/34433809
http://dx.doi.org/10.1038/s41420-021-00608-8