Excitatory synapses and gap junctions cooperate to improve Pv neuronal burst firing and cortical social cognition in Shank2-mutant mice

NMDA receptor (NMDAR) and GABA neuronal dysfunctions are observed in animal models of autism spectrum disorders, but how these dysfunctions impair social cognition and behavior remains unclear. We report here that NMDARs in cortical parvalbumin (Pv)-positive interneurons cooperate with gap junctions...

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Detalles Bibliográficos
Autores principales: Lee, Eunee, Lee, Seungjoon, Shin, Jae Jin, Choi, Woochul, Chung, Changuk, Lee, Suho, Kim, Jihye, Ha, Seungmin, Kim, Ryunhee, Yoo, Taesun, Yoo, Ye-Eun, Kim, Jisoo, Noh, Young Woo, Rhim, Issac, Lee, Soo Yeon, Kim, Woohyun, Lee, Taekyung, Shin, Hyogeun, Cho, Il-Joo, Deisseroth, Karl, Kim, Sang Jeong, Park, Joo Min, Jung, Min Whan, Paik, Se-Bum, Kim, Eunjoon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8387434/
https://www.ncbi.nlm.nih.gov/pubmed/34433814
http://dx.doi.org/10.1038/s41467-021-25356-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8387434/
https://www.ncbi.nlm.nih.gov/pubmed/34433814
http://dx.doi.org/10.1038/s41467-021-25356-2

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