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Na(V)1.5 knockout in iPSCs: a novel approach to study Na(V)1.5 variants in a human cardiomyocyte environment

Cardiomyocytes derived from patient-specific induced pluripotent stem cells (iPSC-CMs) successfully reproduce the mechanisms of several channelopathies. However, this approach involve cell reprogramming from somatic tissue biopsies or genomic editing in healthy iPSCs for every mutation found and to...

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Detalles Bibliográficos
Autores principales:	Pierre, Marion, Djemai, Mohammed, Poulin, Hugo, Chahine, Mohamed
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8387439/ https://www.ncbi.nlm.nih.gov/pubmed/34433864 http://dx.doi.org/10.1038/s41598-021-96474-6

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