Cargando…

Designer Membraneless Organelles Sequester Native Factors for Control of Cell Behavior

Subcellular compartmentalization of macromolecules increases flux and prevents inhibitory interactions to control biochemical reactions. Inspired by this functionality, we sought to build designer compartments that function as hubs to regulate the flow of information through cellular control systems...

Descripción completa

Detalles Bibliográficos
Autores principales: Garabedian, Mikael V., Wang, Wentao, Dabdoub, Jorge B., Tong, Michelle, Caldwell, Reese M., Benman, William, Schuster, Benjamin S., Deiters, Alexander, Good, Matthew C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8387445/
https://www.ncbi.nlm.nih.gov/pubmed/34341589
http://dx.doi.org/10.1038/s41589-021-00840-4