Comprehensive mapping of SARS-CoV-2 interactions in vivo reveals functional virus-host interactions

SARS-CoV-2 is a major threat to global health. Here, we investigate the RNA structure and RNA-RNA interactions of wildtype (WT) and a mutant (Δ382) SARS-CoV-2 in cells using Illumina and Nanopore platforms. We identify twelve potentially functional structural elements within the SARS-CoV-2 genome, o...

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Detalles Bibliográficos
Autores principales: Yang, Siwy Ling, DeFalco, Louis, Anderson, Danielle E., Zhang, Yu, Aw, Jong Ghut Ashley, Lim, Su Ying, Lim, Xin Ni, Tan, Kiat Yee, Zhang, Tong, Chawla, Tanu, Su, Yan, Lezhava, Alexander, Merits, Andres, Wang, Lin-Fa, Huber, Roland G., Wan, Yue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8387478/
https://www.ncbi.nlm.nih.gov/pubmed/34433821
http://dx.doi.org/10.1038/s41467-021-25357-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8387478/
https://www.ncbi.nlm.nih.gov/pubmed/34433821
http://dx.doi.org/10.1038/s41467-021-25357-1

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