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DNA Damage Repair Profiles Alteration Characterize a Hepatocellular Carcinoma Subtype With Unique Molecular and Clinicopathologic Features

Hepatocellular carcinoma (HCC) is one of the most common malignancies and displays high heterogeneity of molecular phenotypes. We investigated DNA damage repair (DDR) alterations in HCC by integrating multi-omics data. HCC patients were classified into two heterogeneous subtypes with distinct clinic...

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Detalles Bibliográficos
Autores principales: Lin, Peng, Gao, Rui-zhi, Wen, Rong, He, Yun, Yang, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8387599/
https://www.ncbi.nlm.nih.gov/pubmed/34456923
http://dx.doi.org/10.3389/fimmu.2021.715460