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The therapeutic potential of inhibiting PPARγ phosphorylation to treat type 2 diabetes

A promising approach for treating type 2 diabetes mellitus (T2DM) is to target the Peroxisome Proliferator-Activated Receptor γ (PPARγ) transcription factor, which regulates the expression of proteins critical for T2DM. Mechanisms involved in PPARγ signaling are poorly understood, yet globally incre...

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Detalles Bibliográficos
Autores principales: Frkic, Rebecca L., Richter, Katharina, Bruning, John B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8387755/
https://www.ncbi.nlm.nih.gov/pubmed/34339734
http://dx.doi.org/10.1016/j.jbc.2021.101030