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The therapeutic potential of inhibiting PPARγ phosphorylation to treat type 2 diabetes
A promising approach for treating type 2 diabetes mellitus (T2DM) is to target the Peroxisome Proliferator-Activated Receptor γ (PPARγ) transcription factor, which regulates the expression of proteins critical for T2DM. Mechanisms involved in PPARγ signaling are poorly understood, yet globally incre...
Autores principales: | Frkic, Rebecca L., Richter, Katharina, Bruning, John B. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8387755/ https://www.ncbi.nlm.nih.gov/pubmed/34339734 http://dx.doi.org/10.1016/j.jbc.2021.101030 |
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