Cargando…

High Glucose Induced Changes in Human VEC Phenotype in a 3D Hydrogel Derived From Cell-Free Native Aortic Root

Background: Valvular endothelial cells (VEC) have key roles in maintaining valvular integrity and homeostasis, and dysfunctional VEC are the initiators and major contributors to aortic valve disease in diabetes. Previous studies have shown that HG stimulated an inflammatory phenotype in VEC. Inflamm...

Descripción completa

Detalles Bibliográficos
Autores principales: Cecoltan, Sergiu, Ciortan, Letitia, Macarie, Razvan D., Vadana, Mihaela, Mihaila, Andreea C., Tucureanu, Monica, Vlad, Mihaela-Loredana, Droc, Ionel, Gherghiceanu, Mihaela, Simionescu, Agneta, Simionescu, Dan Teodor, Butoi, Elena, Manduteanu, Ileana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8387830/
https://www.ncbi.nlm.nih.gov/pubmed/34458339
http://dx.doi.org/10.3389/fcvm.2021.714573